Plant Comparison

Agrimony vs Tormentil

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant

Second plant

Plant AAgrimonyAgrimonia eupatoriaRosaceaeFull monograph →

Plant BTormentilPotentilla erectaRosaceaeFull monograph →

At a glance

Agrimony and Tormentil: both belong to the Rosaceae family; they share 6 indicated uses (arthritis / joint pain, diarrhoea, inflammation (general), …); 3 pharmacological actions in common.

AgrimonyTormentil

Constituents42

Pharmacological actions83

Indicated uses117

Safety notes32

Cited sources1915

Indicated uses

Only Agrimony

Loss of appetiteBloatingBruisingCancer (anticancer research)Indigestion

Shared (6)

Arthritis / joint painDiarrhoeaInflammation (general)Skin irritationSore throatWounds

Only Tormentil

Inflammatory bowel disease (IBD)

Pharmacological actions

Only Agrimony

Anticancer (preclinical)AntioxidantBitter digestive tonic / stomachicDigestive aidVulnerary (wound healing)

Shared (3)

Anti-inflammatoryAntidiarrhoealAstringent

Only Tormentil

none

Evidence face-off — shared uses

Condition	Agrimony	Tormentil	Verdict
Arthritis / joint pain	2/10	1/10	Comparable evidence
Diarrhoea	1/10	5/10	Stronger for Tormentil
Inflammation (general)	2/10	3/10	Comparable evidence
Skin irritation	1/10	6/10	Stronger for Tormentil
Sore throat	2/10	2/10	Comparable evidence
Wounds	2/10	5/10	Stronger for Tormentil

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Tannins (condensed and hydrolysable, including agrimoniin)^{[6, 9, 13, 14]}

Responsible for the characteristic astringency.

Tannins

Flavonoids (luteolin, apigenin, quercetin and their glycosides)^{[9, 14, 15]}

Antioxidant and anti-inflammatory constituents.

FlavonoidsGlycosidesQuercetinApigeninLuteolin

Phenolic acids^{[10, 14]}

Contribute to antioxidant activity.

Phenolic acids

Triterpenes, volatile oil and silica^{[14, 15]}

Minor constituents of the herb.

Essential (volatile) oilTerpenes / terpenoidsSilica

Tannins (ellagitannins such as agrimoniin, and catechin-type tannins)^{[14, 15]}

The main astringent active constituents.

TanninsCatechins

Flavonoids and phenolic acids^[15]

Antioxidant supporting constituents.

Phenolic acidsFlavonoids

Pharmacological Actions

Anti-inflammatory^{[1, 2, 4, 7, 11, 13, 15, 16]}

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Anticancer (preclinical)^[17]

Agrimonia eupatoria ethanolic extract is cytotoxic to breast, colon, lung and cervical cancer cells and inhibits the PI3K/Akt/mTOR pathway (preclinical/in silico).

Antidiarrhoeal^{[13, 14, 15]}

Astringent (relief of mild diarrhoea)

Antioxidant^{[1, 2, 5, 7, 10, 11, 12, 14, 18]}

Astringent^{[13, 14, 15]}

Astringent (relief of mild diarrhoea)

Bitter digestive tonic / stomachic^{[14, 15, 18]}

Mild bitter digestive tonic (indigestion)

Digestive aid^{[14, 15, 18]}

Mild bitter digestive tonic (indigestion)

Vulnerary (wound healing)^{[2, 13, 14, 19]}

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Anti-inflammatory^{[1, 4, 6, 9, 10, 14, 15]}

Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat

Antidiarrhoeal^{[1, 4, 8, 14, 15]}

Astringent for mild diarrhoea (ellagitannins tighten the gut lining) - in a paediatric RCT, tormentil root extract shortened rotavirus diarrhoea (3 vs 5 days) and reduced rehydration needs

Astringent^{[2, 4, 7, 8, 13, 14, 15]}

Astringent for mild diarrhoea (ellagitannins tighten the gut lining) - in a paediatric RCT, tormentil root extract shortened rotavirus diarrhoea (3 vs 5 days) and reduced rehydration needs

Traditional & Indicated Uses

Loss of appetite^{[14, 15, 18]}Traditional · 2/10

inferred from bitter-tonic action

Evidence: 2

Label: Loss of appetite

Arthritis / joint pain^{[1, 2, 13, 15, 16]}Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2

Label: Arthritis / joint pain

Bloating^{[14, 15, 18]}Traditional · 2/10

inferred from digestive action

Evidence: 2

Label: Bloating

Bruising^{[2, 13, 14, 19]}Traditional · 2/10

inferred from vulnerary action

Evidence: 2

Label: Bruising

Cancer (anticancer research)^[17]Traditional · 2/10

Agrimonia eupatoria ethanolic extract shows dose-dependent cytotoxicity against MCF-7 (breast), HT-29 (colon), A549 (lung) and HeLa (cervical) cancer cells and inhibits the PI3K/Akt/mTOR/COX-2/MMP-2 axis (preclinical).

Evidence: 2

Label: Cancer (anticancer research)

Diarrhoea^{[13, 14, 15]}Traditional · 1/10

Astringent (relief of mild diarrhoea)

Evidence: 1

Label: Diarrhoea

Indigestion^{[14, 15, 18]}Traditional · 2/10

Mild bitter digestive tonic (indigestion)

Evidence: 2

Label: Indigestion

Inflammation (general)^{[1, 2, 13, 14, 15, 16, 19]}Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat); Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2

Label: Inflammation (general)

Skin irritation^{[13, 14, 15]}Traditional · 1/10

inferred from astringent action

Evidence: 1

Label: Skin irritation

Sore throat^{[1, 2, 13, 15, 16]}Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Evidence: 2

Label: Sore throat

Wounds^{[2, 13, 14, 19]}Traditional · 2/10

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2

Label: Wounds

Arthritis / joint pain^{[14, 15]}Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1

Label: Arthritis / joint pain

Diarrhoea^{[1, 4, 8, 14, 15]}Moderate · 5/10

Astringent for mild diarrhoea (ellagitannins tighten the gut lining) - in a paediatric RCT, tormentil root extract shortened rotavirus diarrhoea (3 vs 5 days) and reduced rehydration needs

Evidence: 5

Label: Diarrhoea

Inflammatory bowel disease (IBD)^{[9, 11, 15]}Limited · 3/10

Supportive in inflammatory bowel disease / ulcerative colitis (limited trial evidence)

Evidence: 3

Label: Inflammatory bowel disease (IBD)

Inflammation (general)^{[4, 10, 14, 15]}Limited · 3/10

Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat

Evidence: 3

Label: Inflammation (general)

Skin irritation^{[6, 8, 10, 14, 15]}Moderate · 6/10

inferred from astringent action

Evidence: 6

Label: Skin irritation

Sore throat^{[7, 13, 14, 15]}Traditional · 2/10

Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat

Evidence: 2

Label: Sore throat

Wounds^{[8, 14, 15]}Moderate · 5/10

inferred from astringent action

Evidence: 5

Label: Wounds

Safety, Cautions & Contraindications

Safety note^[13]Info

Traditional-use indication only: if diarrhoea persists longer than 3-4 days, or symptoms of mouth/throat inflammation persist beyond about a week, a doctor should be consulted.

Safety note^[13]Caution

Use during pregnancy and breastfeeding is not recommended, as safety has not been established.

Safety note^{[13, 15]}Info

Tannin-rich; very high or prolonged intake may cause gastrointestinal upset or constipation and can reduce the absorption of iron and some medicines taken at the same time.

Safety note^[14]Info

Tannin-rich: high or prolonged intake may cause stomach upset or constipation and can reduce the absorption of iron and some medicines taken at the same time.

Safety note^[14]Caution

Diarrhoea persisting more than 3-4 days, or with fever or blood in the stool, needs medical care. Use in pregnancy and breastfeeding is not recommended in the absence of data.

External Ids

Gbif: 3001956

Wikidata: Q156865

Gbif: 5365576

Wikidata: Q160098

Botanical Description

Slender, downy perennial herb with a basal rosette of pinnately compound leaves and a single, unbranched, upright flowering stem. The leaflets are toothed, alternating large and small, and silvery-downy beneath. Small, five-petalled, bright yellow flowers are borne closely along a slender terminal spike (raceme), opening a few at a time from the base upwards, giving the old name 'church steeples'. After flowering, small bristly, hooked burrs form that cling to clothing and animal fur for dispersal.^{[13, 14]}

Height: 30-100 cm

Habit: Erect, downy perennial herb

Leaves: Pinnately compound, toothed leaflets of alternating large and small size, silvery-downy beneath

Flowers: Small, five-petalled, bright yellow flowers crowded on a slender terminal spike

Stem: Single, unbranched, upright, downy flowering stem

Root: Woody rootstock

Fruit: Small bristly, hooked burr that clings to clothing and fur

Flowering Period: June-September

Low, sprawling to semi-erect perennial herb (Rosaceae) with wiry stems. Leaves are palmate, typically with 4-5 leaflets and large leaf-like stipules that give the impression of more leaflets. Flowers are small, yellow and four-petalled - unusual among Potentilla species, most of which have five petals. The thick, woody rhizome is reddish inside when cut, the origin of the old name 'bloodroot' for this European species.^[14]

Height: Low, sprawling to semi-erect, stems to about 30-45 cm

Habit: Low, sprawling to semi-erect perennial herb

Leaves: Palmate, typically 4-5 leaflets, with large leaf-like stipules

Flowers: Small, yellow, four-petalled (unusual among Potentilla species)

Stem: Wiry, sprawling to semi-erect

Root: Thick, woody rhizome, reddish inside when cut

Fruit: Small dry achenes (typical Rosaceae)

Flowering Period: May-September

Habitat

Grows in dry grassland, hedgerows, field margins, roadsides and open woodland edges on well-drained, often calcareous soils; native and common throughout Europe, temperate Asia and North Africa.^{[13, 14]}

Native to Europe and western Asia, common in acidic grassland, heath, moorland, open woodland and pastures on poor, well-drained soils.^[14]

Harvesting

The flowering aerial parts are cut in summer, at the start of flowering, and dried promptly in a warm, airy, shaded place.^[13]

Parts: Aerial parts (flowering herb)

Season: Summer, at the start of flowering

The rhizome is dug in autumn or early spring, when tannin content is highest, then cleaned and dried.^[14]

Parts: Rhizome

Season: Autumn or early spring

Traditional Uses

Agrimony has a long folk history as an astringent remedy for mild diarrhoea, as a gargle for sore throats and mild mouth/throat inflammation, and as a mild bitter digestive tonic; it has also been applied topically to minor wounds and skin inflammation. It is officially recognised in the European Union herbal monograph for traditional use in mild diarrhoea and mild inflammation of the mouth or throat.^{[13, 14]}

Tormentil rhizome has an official European herbal-monograph tradition for mild diarrhoea and inflammation of the mouth and throat, reflecting its long folk use as a powerful astringent for gut and mucous-membrane complaints. Modern trials confirm its ellagitannin-rich rhizome shortens the duration of infectious (rotavirus) diarrhoea.^{[8, 14, 15]}

Preparations

Infusion^[13]

Dried flowering herb infused in hot water, taken internally for mild diarrhoea and digestive complaints or used as a gargle/mouthwash for sore throat.

Poultice/compress^[13]

Crushed or infused herb applied externally to minor wounds and skin inflammation.

Decoction^[14]

Dried rhizome simmered in water, the standard astringent preparation for diarrhoea.

Tincture^[15]

Alcoholic extract, taken diluted or used as a gargle/mouthwash.

Gargle/mouthwash^[15]

Diluted decoction or tincture used for sore throat and mouth inflammation.

Dosage

Infusion^[13]

The EU herbal monograph gives 1.5-4 g of the comminuted herb in 250 mL (or less) of boiling water as an infusion, 2-3 times daily, in adolescents, adults and elderly. As a gargle for mild oral or throat inflammation, 1.5 g in 150 mL of boiling water 2-4 times daily, or a decoction of 3-4.5 g in 250 mL 2-3 times daily. Educational reference only, not a prescription.

Tincture^[13]

The EU herbal monograph gives 1-4 mL three times daily (orally, or as a gargle for oral and throat use). Educational reference only, not a prescription.

Decoction/tincture^{[14, 15]}

EMA/ESCOP guidance suggests around 4-6 g dried rhizome (or an equivalent decoction), divided into 2-3 doses daily, for diarrhoea, or a diluted tincture used as a gargle several times daily. Educational reference only, not a prescription.

References

REF-0681, REF-0683, REF-2328, REF-2329, REF-2330, REF-2331, REF-2332, REF-2333, REF-2334, REF-2335, REF-2336, REF-2337

REF-0970, REF-0971, REF-0972, REF-0973, REF-0974, REF-0975, REF-0976, REF-0602, REF-0977, REF-0978, REF-2592, REF-2593, REF-2594

Lookalikes Review

Outcome: none-known

Reviewed By: Omnia Sana (owner-authorized)

Reviewed Date: 2026-07-07

Outcome: none-known

Reviewed By: Omnia Sana (owner-authorized)

Reviewed Date: 2026-07-07

References & Sources

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https://www.ema.europa.eu/en/medicines/herbal/agrimoniae-herba
(2022) 'Agrimonia eupatoria L.: An integrative perspective on ethnomedicinal use, phenolic composition and pharmacological activity', Journal of Ethnopharmacology. doi:10.1016/j.jep.2022.115498 Traditional / reference
https://doi.org/10.1016/j.jep.2022.115498
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Shareef, S.H., Asaad, N.K., Gheni, N.A., Fisal, D.N., Shakir Agha, N.F., Ali, R.T. and Abdulla, M.A (2025) 'Agrimonia eupatoria leaf extract attenuates alcohol-induced oxidative stress, ulcer and alleviates stomach damage in rats', Food Science and Nutrition, 13(11). doi:10.1002/fsn3.71203 Preclinical
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https://www.ema.europa.eu/en/medicines/herbal/tormentillae-rhizoma
ESCOP (European Scientific Cooperative on Phytotherapy) (n.d.) 'Tormentillae rhizoma (Tormentil) monograph', pp. com. Available at: https://www.escop.com/downloads/tormentil/ Traditional / reference
https://www.escop.com/downloads/tormentil/

Agrimony monograph Tormentil monograph Compare other plants

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.