← Reference Library

Sesquiterpenoids from Tussilago farfara inhibit LPS-induced nitric oxide production in macrophage RAW 264.7 cells

Jang, H., Lee, J.W., Lee, C., Jin, Q. and others · Archives of Pharmacal Research · 2016

Preclinical

Abstract

A new oplopane-type sesquiterpenoid (tussilagofarin) and a new chromone, together with 18 known compounds, were isolated from the flower buds of Tussilago farfara. Several sesquiterpenoids significantly inhibited LPS-induced nitric oxide production in RAW 264.7 macrophages, demonstrating the anti-inflammatory activity of coltsfoot constituents.

Referenced for these plants

How to cite

Jang, H., Lee, J.W., Lee, C., Jin, Q. and others (2016) 'Sesquiterpenoids from Tussilago farfara inhibit LPS-induced nitric oxide production in macrophage RAW 264.7 cells', Archives of Pharmacal Research, 39(1), pp. 127-132. doi:10.1007/s12272-015-0667-7

This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.