Supercritical CO2 extract and essential oil of aerial part of Ledum palustre L. - Chemical composition and anti-inflammatory activity
Abstract
The anti-inflammatory activity of supercritical-CO2 and hydrodistilled essential oils from the aerial parts of Ledum palustre (Rhododendron tomentosum) was evaluated. Both oils, dominated by ledol and ascaridole, significantly inhibited carrageenan-induced hind-paw oedema in rats (50-80%), comparable to the reference drugs piroxicam and ketoprofen, demonstrating the anti-inflammatory activity of the plant's essential oil.
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How to cite
Baananou, S., Bagdonaite, E., Marongiu, B., Piras, A. and others (2014) 'Supercritical CO2 extract and essential oil of aerial part of Ledum palustre L. - Chemical composition and anti-inflammatory activity', Natural Product Research, 29(11), pp. 999-1005. doi:10.1080/14786419.2014.965167
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