Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes
Abstract
Rhododendron tomentosum is traditionally used for rheumatic complaints, making it a candidate for rheumatoid arthritis (RA) treatment. Essential oils of defined chemotypes were tested on peripheral blood lymphocytes and RA synoviocytes; the oils dose-dependently inhibited lymphocyte proliferation and increased apoptosis/necrosis of RA synovial fibroblasts, supporting anti-arthritic activity.
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How to cite
Jesionek, A., Kokotkiewicz, A., Mikosik-Roczynska, A., Ciesielska-Figlon, K. and others (2019) 'Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes', Fitoterapia, 139, pp. 104402. doi:10.1016/j.fitote.2019.104402
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