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Anti-Inflammatory and Anti-Acne Effects of Hamamelis virginiana Bark in Human Keratinocytes

Piazza, S., Martinelli, G., Vrhovsek, U., Masuero, D. et al. · Antioxidants (Basel) · 2022

Preclinical
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Abstract

A glycolic extract from Hamamelis virginiana bark (rich in hamamelitannin and proanthocyanidins) was evaluated against Cutibacterium acnes- and TNF-alpha-induced inflammation in human keratinocytes. The extract inhibited IL-6 and IL-8 release by partially impairing NF-kB activation and acting through antioxidant mechanisms, supporting the use of witch hazel for inflammatory skin conditions such as acne.

Referenced for these plants

Common witch hazelSnapping hazelnutWinterbloomWitch HazelHamamelis virginiana

How to cite

Piazza, S., Martinelli, G., Vrhovsek, U., Masuero, D. et al (2022) 'Anti-Inflammatory and Anti-Acne Effects of Hamamelis virginiana Bark in Human Keratinocytes', Antioxidants (Basel), 11(6), pp. 1119. doi:10.3390/antiox11061119

This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.

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