Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMP-Activated Protein Kinase Signaling Pathway
Abstract
Cordycepin, a natural product isolated from Cordyceps militaris, was evaluated in mice with diet-induced nonalcoholic steatohepatitis (NASH). Cordycepin attenuated hepatic lipid accumulation, inflammation, liver injury and fibrosis through activation of the AMP-activated protein kinase (AMPK) signaling pathway, suggesting cordycepin as a potential AMPK-activating treatment for NASH.
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How to cite
Lan, T., Yu, Y., Zhang, J., Li, H. et al (2021) 'Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMP-Activated Protein Kinase Signaling Pathway', Hepatology, 74(2), pp. 686-703. doi:10.1002/hep.31749
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