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Gastroprotective effect of small centaury (Centaurium erythraea L) on aspirin-induced gastric damage in rats

Tuluce, Y., Ozkol, H., Koyuncu, I. and Ine, H. · Toxicology and Industrial Health · 2011

Preclinical

Abstract

The gastroprotective and antioxidant activity of a 50% aqueous-ethanolic Centaurium erythraea (small centaury) extract was investigated in an aspirin-induced acute gastric ulcer model in rats. The centaury extract significantly reduced the ulcer index by 77% versus aspirin alone, raised glutathione and vitamin A and lowered lipid peroxidation and myeloperoxidase, indicating protection against gastric damage through antioxidant activity, supporting its traditional digestive use.

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How to cite

Tuluce, Y., Ozkol, H., Koyuncu, I. and Ine, H (2011) 'Gastroprotective effect of small centaury (Centaurium erythraea L) on aspirin-induced gastric damage in rats', Toxicology and Industrial Health, 27(8), pp. 760-768. doi:10.1177/0748233710397421

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