Water Extract of Capsella bursa-pastoris Mitigates Doxorubicin-Induced Cardiotoxicity by Upregulating Antioxidant Enzymes
Abstract
A hot-water extract of Capsella bursa-pastoris (CBW), containing flavonoids such as luteolin-7-O-glucoside and isoorientin, protected H9c2 cardiomyocytes and mouse hearts from doxorubicin-induced cardiotoxicity by increasing superoxide dismutase, reducing reactive oxygen species and recovering cardiac electrophysiology, without protecting breast cancer cells, suggesting potential as an adjunct that mitigates chemotherapy cardiotoxicity.
Referenced for these plants
How to cite
Jeong, Y., Lee, S.H., Lee, J., Kim, M.S. et al (2023) 'Water Extract of Capsella bursa-pastoris Mitigates Doxorubicin-Induced Cardiotoxicity by Upregulating Antioxidant Enzymes', International Journal of Molecular Sciences, 24(21), pp. 15912. doi:10.3390/ijms242115912
This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.