Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root's hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice
Abstract
Arctium lappa (burdock) root has hypoglycemic and antioxidative effects and has been used for treatment of diabetes in traditional medicine. This study evaluated the antidiabetic and hypolipidemic properties of the root's hydro-alcoholic extract on nicotinamide-streptozotocin-induced type 2 diabetes in male mice. Administration of the extract significantly decreased triglyceride, VLDL, glucose and alkaline phosphatase, and increased insulin, HDL and leptin levels, indicating an antidiabetic effect through hypolipidemic and insulinotropic properties, and a hepatoprotective effect.
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How to cite
Ahangarpour, A., Heidari, H., Oroojan, A.A., Mirzavandi, F., Nasr Esfehani, K. and Dehghan Mohammadi, Z (2017) 'Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root's hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice', Avicenna Journal of Phytomedicine, 7(2), pp. 169-179. Available at: https://pubmed.ncbi.nlm.nih.gov/28348972/
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