Hypericum perforatum L. attenuates depression by regulating Akkermansia muciniphila, tryptophan metabolism and NFkB-NLRP2-Caspase1-IL1beta pathway
Preclinical
Abstract
Hypericum perforatum attenuated depressive behaviour in mice by regulating the gut bacterium Akkermansia muciniphila, tryptophan metabolism and the NF-kB-NLRP2-Caspase1-IL1beta inflammatory pathway, linking its antidepressant and anti-inflammatory actions.
Referenced for these plants
How to cite
Jiang, Z., Wang, F., Zhao, Y., Lu, L., Jiang, X., Huang, T., Lin, Y., Guo, L., Weng, Z. and Liu, E (2024) 'Hypericum perforatum L. attenuates depression by regulating Akkermansia muciniphila, tryptophan metabolism and NFkB-NLRP2-Caspase1-IL1beta pathway', Phytomedicine, 132, pp. 155847. doi:10.1016/j.phymed.2024.155847
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