Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Preclinical
Abstract
A parthenolide-depleted extract of feverfew (Tanacetum parthenium) inhibited 5-lipoxygenase and phosphodiesterases and reduced release of pro-inflammatory mediators (nitric oxide, PGE2, TNF-alpha) from macrophages and PBMCs, and reduced dermatitis in vivo, demonstrating potent anti-inflammatory activity without skin sensitization.
Referenced for these plants
How to cite
Sur, R., Martin, K., Liebel, F., Lyte, P. and others (2009) 'Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)', Inflammopharmacology, 17(1), pp. 42-49. doi:10.1007/s10787-008-8040-9
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