Antiproliferative and apoptotic effects of the herbal agent Pygeum africanum on cultured prostate stromal cells from patients with benign prostatic hyperplasia (BPH)
Abstract
Pygeum (Prunus africana) was antiproliferative and pro-apoptotic on prostate stromal fibroblasts/myofibroblasts from benign-prostatic-hyperplasia patients, via TGF-beta1 down-regulation and FGF2-signalling inhibition, providing a mechanism for its prostate-supporting, anti-inflammatory action.
Referenced for these plants
How to cite
Quiles, M.T., Arbos, M.A., Fraga, A., de Torres, I.M. and others (2010) 'Antiproliferative and apoptotic effects of the herbal agent Pygeum africanum on cultured prostate stromal cells from patients with benign prostatic hyperplasia (BPH)', The Prostate, 70(10), pp. 1044-1053. doi:10.1002/pros.21138
This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.