The comparative toxicity of a reduced, crude comfrey (Symphytum officinale) alkaloid extract and the pure, comfrey-derived pyrrolizidine alkaloids, lycopsamine and intermedine in chicks (Gallus gallus domesticus)
Abstract
The toxicity of a crude comfrey (Symphytum officinale) pyrrolizidine-alkaloid extract and the pure alkaloids lycopsamine and intermedine was compared in chicks, characterising the hepatotoxic potential that underlies the safety restrictions on internal comfrey use.
Referenced for these plants
How to cite
Brown, A.W., Stegelmeier, B.L., Colegate, S.M., Gardner, D.R. and others (2016) 'The comparative toxicity of a reduced, crude comfrey (Symphytum officinale) alkaloid extract and the pure, comfrey-derived pyrrolizidine alkaloids, lycopsamine and intermedine in chicks (Gallus gallus domesticus)', Journal of Applied Toxicology, 36(5), pp. 716-725. doi:10.1002/jat.3205
This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.