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A new withanolide from Saponaria officinalis and its antimicrobial and cytotoxic activities

Ashurova, L.N., Khurramov, A.R., Bobakulov, K.M., Sasmakov, S.A. and others · Natural Product Research · 2025

Preclinical

Abstract

A new withanolide and two known compounds (gracillin and 5-alpha-hydroxylaxogenin) were isolated from the aerial part of Saponaria officinalis. The new withanolide showed antimicrobial activity against several bacterial strains and significant cytotoxicity against HEp-2 and HeLa cancer cell lines.

Referenced for these plants

How to cite

Ashurova, L.N., Khurramov, A.R., Bobakulov, K.M., Sasmakov, S.A. and others (2025) 'A new withanolide from Saponaria officinalis and its antimicrobial and cytotoxic activities', Natural Product Research, 40(9), pp. 2392-2401. doi:10.1080/14786419.2025.2472276

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