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Omnia Sana · Plant Monograph

Purple coneflower

Echinacea purpurea

Family AsteraceaeParts used Flower, RootAlso known as Snakeroot, Black Sampson

This monograph compiles 3 pharmacological actions, 7 traditional / indicated uses, supported by 17 cited sources, drawn directly from the Omnia Sana plant database.

Pharmacological Actions

Anti-inflammatory[4, 11, 15, 16, 17]
Antimicrobial[7, 8, 10, 15, 16, 17]
Immunomodulator / immune support[4, 5, 6, 8, 9, 15, 16, 17]

Traditional & Indicated Uses

Arthritis / joint pain[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

more plants for arthritis / joint pain →detailed sources →
Cold & flu[15, 16, 17]Traditional · 1/10

inferred from immunomodulator action

more plants for cold & flu →detailed sources →
Immune support[15, 16, 17]Traditional · 1/10
more plants for immune support →detailed sources →
Infection (general)[15, 16, 17]Traditional · 1/10

inferred from antimicrobial action

more plants for infection (general) →detailed sources →
Inflammation (general)[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

more plants for inflammation (general) →detailed sources →
Skin irritation[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

more plants for skin irritation →detailed sources →
Wounds[15, 16, 17]Traditional · 1/10

inferred from antimicrobial action

more plants for wounds →detailed sources →

Safety, Cautions & Contraindications

Safety note[15, 16, 17]Caution

Generally considered safe, but caution advised for those with autoimmune conditions. Not recommended for long-term use (more than 8 weeks continuously).

Safety note[15, 16, 17]Caution

Duke (2002) rates echinacea as +++ — among the most thoroughly documented herbal immunostimulants. It notes experimental and clinical evidence for immunostimulant, antiviral, and anti-inflammatory activities. Multiple species have been studied (E. purpurea, E. angustifolia, E. pallida), and Duke emphasizes that species identification in commercial products is often unreliable. Commission E approves E. purpurea for supporting immune function during colds and flu. Dose: 900 mg standardized extract daily in acute use; use should be limited to 8 weeks continuous. Contraindicated in autoimmune diseases (MS, lupus, HIV/AIDS), tuberculosis, and with immunosuppressive drugs (cyclosporine) (Duke, 2002).

References

REF-0797, REF-0798, REF-0799, REF-2011, REF-2012, REF-2013, REF-2014, REF-2015, REF-2016, REF-2017, REF-2018, REF-2019, REF-2020, REF-2021

References & Sources

  1. Karsch-Völk, M., Barrett, B., Kiefer, D., Bauer, R. et al (2014) 'Echinacea for preventing and treating the common cold', Cochrane Database of Systematic Reviews, 2(2), pp. CD000530. doi:10.1002/14651858.CD000530.pub3 Meta-analysis / review
    https://doi.org/10.1002/14651858.CD000530.pub3
  2. Kamin, W., Seifert, G., Zwiauer, K., Bonhoeffer, J. et al (2025) 'Phytotherapy for acute respiratory tract infections in children: a systematically conducted, comprehensive review', Frontiers in Pediatrics, 13, pp. 1423250. doi:10.3389/fped.2025.1423250 Meta-analysis / review
    https://doi.org/10.3389/fped.2025.1423250
  3. Fashner, J., Ericson, K. and Werner, S (2012) 'Treatment of the common cold in children and adults', American Family Physician, 86(2), pp. 153-159. Available at: https://pubmed.ncbi.nlm.nih.gov/22962927/ Traditional / reference
    https://pubmed.ncbi.nlm.nih.gov/22962927/
  4. Manayi, A., Vazirian, M. and Saeidnia, S (2015) 'Echinacea purpurea: Pharmacology, phytochemistry and analysis methods', Pharmacognosy Reviews, 9(17), pp. 63-72. doi:10.4103/0973-7847.156353 Meta-analysis / review
    https://doi.org/10.4103/0973-7847.156353
  5. Burlou-Nagy, C., Banica, F., Jurca, T., Vicas, L.G., Marian, E., Muresan, M.E., Bacskay, I., Kiss, R., Feher, P. and Pallag, A (2022) 'Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review', Plants, 11(9), pp. 1244. doi:10.3390/plants11091244 Meta-analysis / review
    https://doi.org/10.3390/plants11091244
  6. Hall, H., Fahlman, M.M. and Engels, H.J (2007) 'Echinacea purpurea and mucosal immunity', International Journal of Sports Medicine, 28(9), pp. 792-797. doi:10.1055/s-2007-964895 Randomized trial
    https://doi.org/10.1055/s-2007-964895
  7. Ross, S.M (2016) 'Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold', Holistic Nursing Practice, 30(1), pp. 54-57. doi:10.1097/HNP.0000000000000130 Meta-analysis / review
    https://doi.org/10.1097/HNP.0000000000000130
  8. Hudson, J.B (2011) 'Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases', Journal of Biomedicine & Biotechnology, 2012, pp. 769896. doi:10.1155/2012/769896 Meta-analysis / review
    https://doi.org/10.1155/2012/769896
  9. Mishima, S., Saito, K., Maruyama, H., Inoue, M., Yamashita, T., Ishida, T. and Gu, Y (2004) 'Antioxidant and immuno-enhancing effects of Echinacea purpurea', Biological & Pharmaceutical Bulletin, 27(7), pp. 1004-1009. doi:10.1248/bpb.27.1004 Preclinical
    https://doi.org/10.1248/bpb.27.1004
  10. Saunders, P.R., Smith, F. and Schusky, R.W (2007) 'Echinacea purpurea L. in children: safety, tolerability, compliance, and clinical effectiveness in upper respiratory tract infections', Canadian Journal of Physiology and Pharmacology, 85(11), pp. 1195-1199. doi:10.1139/Y07-103 Clinical study
    https://doi.org/10.1139/Y07-103
  11. Micheli, L., Maggini, V., Ciampi, C., Gallo, E., Bogani, P., Fani, R., Pistelli, L., Ghelardini, C., Di Cesare Mannelli, L., De Leo, M. and Firenzuoli, F (2022) 'Echinacea purpurea against neuropathic pain: Alkamides versus polyphenols efficacy', Phytotherapy Research, 37(5), pp. 1911-1923. doi:10.1002/ptr.7709 Preclinical
    https://doi.org/10.1002/ptr.7709
  12. Gholami, M., Amri, J., Pazhoohan, S. and Sadegh, M (2021) 'Anticonvulsive and anti-epileptogenesis effects of Echinacea purpurea root extract, an involvement of CB2 receptor', Journal of Complementary & Integrative Medicine, 19(4), pp. 879-886. doi:10.1515/jcim-2020-0219 Preclinical
    https://doi.org/10.1515/jcim-2020-0219
  13. Awortwe, C., Bruckmueller, H., Kaehler, M. and Cascorbi, I (2021) 'Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters', Molecular Pharmaceutics, 18(4), pp. 1622-1633. doi:10.1021/acs.molpharmaceut.0c01075 Preclinical
    https://doi.org/10.1021/acs.molpharmaceut.0c01075
  14. Perry, N.B., van Klink, J.W., Burgess, E.J. and Parmenter, G.A (1997) 'Alkamide levels in Echinacea purpurea: a rapid analytical method revealing differences among roots, rhizomes, stems, leaves and flowers', Planta Medica, 63(1), pp. 58-62. doi:10.1055/s-2006-957605 Preclinical
    https://doi.org/10.1055/s-2006-957605
  15. Linde, K., Barrett, B., Wölkart, K., Bauer, R. and Melchart, D (2006) 'Echinacea for preventing and treating the common cold'. Traditional / reference
    Find this source
  16. Sharma, M., Schoop, R., Suter, A. and Schoop, W (2010) 'The possibility of prophylactic treatment of streptococcal pharyngotonsillitis with a standardized Echinacea preparation', 29(8), pp. 1025--1035. Traditional / reference
    Find this source
  17. World Health Organization (1999) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
    Find this source

Record last updated 2026-06-20 · Provenance: book+pubmed · Status: verified

This fact sheet is generated automatically from the Omnia Sana plant database and reflects its latest synced data. It is provided for educational purposes only and is not medical advice. Always consult a qualified practitioner before using medicinal plants.

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