Omnia Sana · Plant Monograph
Olive
Olea europaea
This monograph compiles 5 pharmacological actions, 9 traditional / indicated uses, supported by 13 cited sources, drawn directly from the Omnia Sana plant database.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
more plants for arthritis / joint pain →detailed sources →inferred from antidiabetic action
more plants for blood sugar / diabetes support →detailed sources →inferred from antiviral action
more plants for cold & flu →detailed sources →inferred from antimicrobial action
more plants for infection (general) →detailed sources →inferred from anti-inflammatory action
more plants for inflammation (general) →detailed sources →inferred from antidiabetic action
more plants for metabolic support →detailed sources →inferred from anti-inflammatory action
more plants for skin irritation →detailed sources →inferred from antimicrobial action
more plants for wounds →detailed sources →Safety, Cautions & Contraindications
Olive leaf extract may lower blood pressure; use caution if already on antihypertensive medication. May have mild hypoglycaemic effects. Olive oil is safe for dietary use. Rare olive pollen allergy. Well tolerated in normal culinary and supplement doses.
Duke (2002) includes olive leaf as ++ and notes hypotensive, hypoglycemic, ACE inhibitor-like, and antioxidant activities at the experimental level (score 1). Olive leaf extract (containing oleuropein) has demonstrated blood pressure-lowering and antiarrhythmic effects consistent with clinical support (PHR). Duke notes that traditional Mediterranean use for both the leaf and fruit is food-grade and safe. Olive leaf preparations are used as mild antihypertensives in European phytotherapy. No significant adverse effects are reported at standard herbal doses (Duke, 2002).
References
REF-1437, REF-1438, REF-1439, REF-1440, REF-1441, REF-1442, REF-1443, REF-1444, REF-1445, REF-1446References & Sources
- Omar, S.H., Kerr, P.G., Scott, C.J., Hamlin, A.S. and others (2017) 'Olive (Olea europaea L.) Biophenols: A Nutriceutical against Oxidative Stress in SH-SY5Y Cells', Molecules, 22(11), pp. 1858. doi:10.3390/molecules22111858 Preclinical
https://doi.org/10.3390/molecules22111858 - Ruzzolini, J., Peppicelli, S., Andreucci, E., Bianchini, F. and others (2018) 'Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies', Nutrients, 10(12), pp. 1950. doi:10.3390/nu10121950 Preclinical
https://doi.org/10.3390/nu10121950 - Al-Rimawi, F., Sbeih, M., Amayreh, M., Rahhal, B. and others (2024) 'Evaluation of the antibacterial and antifungal properties of oleuropein, Olea europaea leaf extract, and Thymus vulgaris oil', BMC Complementary Medicine and Therapies, 24(1), pp. 297. doi:10.1186/s12906-024-04596-x Preclinical
https://doi.org/10.1186/s12906-024-04596-x - Qabaha, K., Al-Rimawi, F., Qasem, A. and Naser, S.A (2018) 'Oleuropein Is Responsible for the Major Anti-Inflammatory Effects of Olive Leaf Extract', Journal of Medicinal Food, 21(3), pp. 302-305. doi:10.1089/jmf.2017.0070 Preclinical
https://doi.org/10.1089/jmf.2017.0070 - Pang, K.L., Lumintang, J.N. and Chin, K.Y (2021) 'Thyroid-Modulating Activities of Olive and Its Polyphenols: A Systematic Review', Nutrients, 13(2), pp. 529. doi:10.3390/nu13020529 Meta-analysis / review
https://doi.org/10.3390/nu13020529 - Kheirandish, F., Mosaffa, N., Tarahi, M.J. and Fallahi, S (2018) 'Olive (Olea europaea) leaf extract alters the cytokine profile of Leishmania major-infected macrophages: New insight into the underlying mechanism', Parasite Immunology, 40(4), pp. e12520. doi:10.1111/pim.12520 Preclinical
https://doi.org/10.1111/pim.12520 - de Bock, M., Derraik, J.G., Brennan, C.M., Biggs, J.B. and others (2013) 'Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial', PLoS One, 8(3), pp. e57622. doi:10.1371/journal.pone.0057622 Randomized trial
https://doi.org/10.1371/journal.pone.0057622 - Pasban-Aliabadi, H., Esmaeili-Mahani, S., Sheibani, V., Abbasnejad, M. and others (2013) 'Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein', Rejuvenation Research, 16(2), pp. 134-142. doi:10.1089/rej.2012.1384 Preclinical
https://doi.org/10.1089/rej.2012.1384 - Imperatrice, M., Lasfar, A., van Kalkeren, C.A.J. and Troost, F (2024) 'Olive Leaf Extract Supplementation Improves Postmenopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Parallel Study on Postmenopausal Women', Nutrients, 16(22), pp. 3879. doi:10.3390/nu16223879 Randomized trial
https://doi.org/10.3390/nu16223879 - de Bock, M., Thorstensen, E.B., Derraik, J.G., Henderson, H.V. and others (2013) 'Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract', Molecular Nutrition & Food Research, 57(11), pp. 2079-2085. doi:10.1002/mnfr.201200795 Preclinical
https://doi.org/10.1002/mnfr.201200795 - Boskov Hansen, H.C. et al (2012) 'Oleocanthal, a phenolic derived from virgin olive oil: a review of the beneficial effects on inflammatory disease', 13(9), pp. 11628--11670. Traditional / reference
Find this source - Wainstein, J. et al (2012) 'Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats', 15(7), pp. 605--610. Randomized trial
Find this source - Waterman, E. and Lockwood, B (2007) 'Active components and clinical applications of olive oil', 12(4), pp. 331--342. Preclinical
Find this source
Generated June 22, 2026 from omniasana.bio